A Prevalence Of Chemotherapy Induced Peripheral Neuropathy Among Lymphoma Patients Receiving Abvd And R Chop Chemotherapy At Hematology Unit In Public Hospital
Keywords:chemotherapy induced peripheral neuropathy, lymphoma, chemotherapy, haematology
Introduction: Chemotherapy induced peripheral neuropathy (CIPN) can be recognized as dysfunction of motor, sensory and or autonomic neurons, results in peripheral neuropathic signs and symptoms such as tingling, numbness and burning or shooting pain. CIPN often resulting in serious limitation in daily functioning since it is the main reason for reduction or discontinuation of therapy and symptoms are frequently disabling, and severely impact quality of life. Objective: To determine the demographics factor among lymphoma patient and identify the association between demographics characteristic with CIPN. Methods: Cross sectional study involving 100 respondents of Ampang Hospital. The studied was carried out in Haematology Department in Ampang Hospital from October 2019 until December 2019. Descriptive statistic was used to analyze the demographic factors and Independent T-Test for the research objective on identify the prevalence of CIPN among lymphoma patient. The statistical Chi Square analysis were used for objective in association between demographic characteristics with CIPN. Findings: There is no significant between CIPN and race, diagnosis, regime and age of the respondent in three scales (sensory, motor and autonomic) p>0.05. Significant between CIPN and gender in autonomic scales, and cycles of chemotherapy in sensory and autonomic scales. There is equal proportion of CIPN in age, race, diagnosis, regime and cycles of chemotherapy in sensory, motor and autonomic p>0.05, but the proportion of CIPN is different in gender (autonomic scales) p<0.05.
Keywords: Chemotherapy induced peripheral neuropathy, lymphoma, chemotherapy, haematology